Modeling immune response and its effect on infectious disease outbreak dynamics

TitleModeling immune response and its effect on infectious disease outbreak dynamics
Publication TypeJournal Article
Year of Publication2016
AuthorsReyes-Silveyra J, Mikler AR
JournalTheoretical Biology and Medical Modelling
Volume13
Pagination1–21
Date Published03/2016
ISSN1742-4682
Abstract

In recent epidemiological models, immunity is incorporated as a simplified value that determines the capacity of an individual to become infected or to transmit the disease. Moreover, the quality of the immune response determines the chances of infection and the length of time an individual is capable to infect others. We present a model that incorporates individuals' immune responses to, further, examine the role of the collective immune response of individuals in a population during an infectious outbreak.

URLhttp://dx.doi.org/10.1186/s12976-016-0033-6
DOI10.1186/s12976-016-0033-6